Ivermectin B1a
CAS No. 71827-03-7
Ivermectin B1a( —— )
Catalog No. M27454 CAS No. 71827-03-7
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 335 | Get Quote |
|
10MG | 494 | Get Quote |
|
25MG | 782 | Get Quote |
|
50MG | 1053 | Get Quote |
|
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIvermectin B1a
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NoteResearch use only, not for human use.
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Brief DescriptionIvermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
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DescriptionIvermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.(In Vitro):Ivermectin B1a(0.3 μg/ml) is inactive, whereas in the case of the minor component, ivermectin B1b(0.3 μg/ml) produces 100% mortality of snails.
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In VitroIvermectin belongs to the macrocyclic lactone class of avermectins and consists of a mixture of two homologous compounds, ivermectin B1a (not less than 80%) and ivermectin B1b (not more than 20%). Ivermectin B1a, the major component of Ivermectin, is inactive at a concentration of 0.3 μg/ml, whereas in the case of the minor component, ivermectin B1b, the same concentration produces 100% mortality of snails.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorσ1
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Research Area——
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Indication——
Chemical Information
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CAS Number71827-03-7
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Formula Weight875.09
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Molecular FormulaC48H74O14
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (114.27 mM)
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SMILESCC[C@@H]([C@@H]1[C@@H](C)CC[C@]2(C[C@@H]3C[C@@H](C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6CO[C@H]7[C@]\6(O)[C@H](C(O3)=O)C=C(C)[C@H]7O)O2)O1)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.
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